In case you completed our checklist and the connectivity issue still manifest, please please supply below information when reporting an issue to our support desk:
IP address of the machine where error was observed.
or NAT egress IP as that service appears to outside of your organization.
Integration engine parameters:
Supported TLS versions
Supported cipher suites
Trusted Root CA certs
Target hostname and/or IP you're trying to connect to.
Exact symptom (a stack trace ideally).
These information will help us to quicker troubleshoot root causes.